Escaping from dangerous situations is something all animals have to do. How they do it is a complex question. One group of inhibitory receptors, the GABAA receptors, regulates a long list of circuits and behaviors in vertebrates. I am interested in how these receptors regulate escape behavior. To answer my questions I use zebrafish as a model system. Using a combination of mRNA in situ hybridization, drug treatment, behavioral analysis, and now electrophysiology, I am unraveling how these circuits function or fail to function.
Be sure to check out the links to my current and previous research labs and the UMass Histology Gallery.